The "Flipping effect" refers to a situation in clinical diagnostics where the levels of lactate dehydrogenase (LDH) isoenzymes in the blood show a reversal of the normal pattern. Normally, LDH-2 is greater than LDH-1; however, in some pathological conditions such as myocardial infarction, this pattern is reversed, resulting in LDH-1 being greater than LDH-2, which is termed the "Flipping effect." Therefore, the correct explanation of the "Flipping effect" is represented by the ratio LDH 1 > LDH 2.