Question:

Which arthritis causes NO periosteal reaction?

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The symmetric erosive seropositive arthritis builds no new periosteal bone.
Updated On: Jun 24, 2026
  • Psoriatic arthritis
  • Reactive arthritis
  • Neuropathic arthritis
  • Rheumatoid arthritis
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The Correct Option is D

Solution and Explanation

Step 1: Periosteal reaction is new bone laid down by the periosteum in response to inflammation or injury, and certain arthritides characteristically provoke it while others do not.

Step 2: Psoriatic arthritis, reactive arthritis (Reiter syndrome), and neuropathic arthropathy all typically show periosteal new bone formation on radiographs. The seronegative spondyloarthropathies in particular are known for fluffy or exuberant periostitis.

Step 3: Rheumatoid arthritis is an erosive arthropathy whose hallmarks are juxta-articular osteopenia, symmetrical marginal erosions, joint space narrowing and soft tissue swelling. Importantly it does NOT produce periosteal reaction, which helps distinguish it from the seronegative group.

Step 4: Since the other three options are associated with periostitis, rheumatoid arthritis is the one with no periosteal reaction and is the correct answer.
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