To find the probability of rolling six distinct numbers, calculate the total number of favorable outcomes and divide by the total number of possible outcomes.
Step 1: Total possible outcomes.
\[
6^6 = 46656
\]
Step 2: Favorable outcomes.
The first die can take any of the 6 numbers, the second can take any of the remaining 5, and so on:
\[
6 \cdot 5 \cdot 4 \cdot 3 \cdot 2 \cdot 1 = 720
\]
Step 3: Calculate the probability.
\[
P = \frac{\text{Favorable Outcomes}}{\text{Total Outcomes}} = \frac{720}{46656} = \frac{5}{324}
\]
Final Answer:
\[
\boxed{\frac{5}{324}}
\]