Question:
What is the most common site of a chronic gastric ulcer?
What is the most common site of a chronic gastric ulcer?
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Think of where H. pylori colonizes the stomach.
Updated On: Jun 24, 2026
- Pyloric antrum
- Upper part of lesser curvature
- Lower part of lesser curvature
- Segment of large intestine
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The Correct Option is A
Solution and Explanation
Step 1: Chronic gastric ulcers are strongly linked to Helicobacter pylori, which colonizes the antral mucosa and drives chronic inflammation (responsible for about 60% of gastric and 50 to 75% of duodenal ulcers).
Step 2: Because the antrum is the main site of H. pylori colonization and acid-related mucosal injury, the pyloric antrum (especially along the lesser curvature near the antrum) is the most common site of a chronic gastric ulcer.
Step 3: The large intestine is not a site of gastric ulceration, and the upper or lower lesser curvature alone is less commonly cited than the antrum, making the pyloric antrum the best answer.
Step 2: Because the antrum is the main site of H. pylori colonization and acid-related mucosal injury, the pyloric antrum (especially along the lesser curvature near the antrum) is the most common site of a chronic gastric ulcer.
Step 3: The large intestine is not a site of gastric ulceration, and the upper or lower lesser curvature alone is less commonly cited than the antrum, making the pyloric antrum the best answer.
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