Question:
What is the most common cause for squamous cell carcinoma at the base of the tongue?
What is the most common cause for squamous cell carcinoma at the base of the tongue?
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Base of tongue and tonsillar SCC are commonly linked to HPV, especially HPV-16.
Updated On: May 14, 2026
- EBV
- HPV
- HCV
- CMV
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The Correct Option is B
Solution and Explanation
Concept:
Oropharyngeal squamous cell carcinoma, especially involving the base of tongue and tonsil, is strongly associated with human papillomavirus infection.
Step 1: Identify tumor location.
The base of tongue is part of the oropharynx.
Step 2: Recall viral association.
Oropharyngeal SCC is commonly associated with: \[ \text{HPV} \]
Step 3: Choose correct cause.
Therefore, the most common cause is: \[ \text{Human papillomavirus} \]
Step 1: Identify tumor location.
The base of tongue is part of the oropharynx.
Step 2: Recall viral association.
Oropharyngeal SCC is commonly associated with: \[ \text{HPV} \]
Step 3: Choose correct cause.
Therefore, the most common cause is: \[ \text{Human papillomavirus} \]
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