Question:
What is the characteristic deposit seen in retinal macular degeneration?
What is the characteristic deposit seen in retinal macular degeneration?
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What yellow deposits form between the RPE and Bruch membrane in dry ARMD?
Updated On: Jun 24, 2026
- Iron
- Drusen
- Lipochrome
- Hemosiderin
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The Correct Option is B
Solution and Explanation
Step 1: Age related macular degeneration (ARMD) is a degenerative disease of the central retina that damages central vision. It has a dry (atrophic) form and a wet (exudative) form.
Step 2: The dry form begins with characteristic yellow deposits in the macula called drusen. These are extracellular accumulations of lipid and protein debris that collect between the retinal pigment epithelium and the underlying choroid (Bruch membrane), making drusen the hallmark deposit and the correct answer.
Step 3: The number and size of drusen help grade the disease, and large confluent soft drusen increase the risk of progression to advanced ARMD.
Step 4: The other options are deposits of different diseases. Iron and hemosiderin accumulate after intraocular haemorrhage or a retained iron foreign body (siderosis), while lipochrome is an age pigment unrelated to the defining macular deposit of ARMD.
Step 2: The dry form begins with characteristic yellow deposits in the macula called drusen. These are extracellular accumulations of lipid and protein debris that collect between the retinal pigment epithelium and the underlying choroid (Bruch membrane), making drusen the hallmark deposit and the correct answer.
Step 3: The number and size of drusen help grade the disease, and large confluent soft drusen increase the risk of progression to advanced ARMD.
Step 4: The other options are deposits of different diseases. Iron and hemosiderin accumulate after intraocular haemorrhage or a retained iron foreign body (siderosis), while lipochrome is an age pigment unrelated to the defining macular deposit of ARMD.
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