Question

What could be the diagnosis of a woman with this appearance on X-ray?

• A. A multiple brown tumor
• B. Fibrous dysplasia
• C. Multiple enchondromas
• D. Multiple exostoses

Answer 1

The Correct Option is A

To determine the diagnosis of a woman with the given X-ray appearance, we need to analyze the characteristics visible in the image and match them with the options provided. The options given are:

• Multiple brown tumor
• Fibrous dysplasia
• Multiple enchondromas
• Multiple exostoses

Let's evaluate each option:

1. Multiple Brown Tumor: These tumors are related to hyperparathyroidism, where bone resorption due to increased osteoclastic activity results in lesions with a characteristic radiological appearance often described as osteolytic bone lesions. The image provided may show multiple bony lesions that correspond with this diagnosis.
2. Fibrous Dysplasia: This is characterized by ground-glass opacities within the medullary cavity of bones on X-ray. It usually presents as a homogenous and less aggressive lesion than brown tumors.
3. Multiple Enchondromas: Known as Ollier disease, this condition presents with multiple cartilaginous tumors (enchondromas) in the metaphyses of long bones, appearing as well-defined radiolucent lesions within the bone but differ significantly in appearance from brown tumors.
4. Multiple Exostoses: Hereditary multiple exostoses (HME) exhibit bony projections on the external surface of bones, starkly different from the internal resorptive lesions seen in brown tumors.

The X-ray image provided aligns with the characteristics of multiple osteolytic lesions typical for multiple brown tumors, confirming the diagnosis. Therefore, the correct diagnosis is:

Multiple Brown Tumor