Question:

Third line of defence in human body is:

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First line = Physical barriers, Second line = Innate immunity, Third line = Specific immunity involving antibodies and lymphocytes.
Updated On: Jun 12, 2026
  • Antibodies
  • Phagocytes
  • Lysozyme
  • Fever
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The Correct Option is A

Solution and Explanation

Concept: The immune system protects the body through multiple defensive barriers commonly referred to as lines of defence.

Step 1: First line of defence.
The first line includes physical and chemical barriers such as:
• Skin
• Mucous membranes
• Lysozyme in tears and saliva

Step 2: Second line of defence.
The second line consists of innate immune responses including:
• Phagocytosis
• Inflammation
• Fever

Step 3: Third line of defence.
The third line is specific or acquired immunity. It involves:
• B-lymphocytes
• T-lymphocytes
• Antibody production Antibodies specifically recognize and neutralize antigens.

Step 4: Final conclusion.
The third line of defence is represented by: \[ \boxed{\text{Antibodies}} \] Hence option (A) is correct.
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