The toxic substance 'haemozoin' responsible for high fever and chill, is released in which of the following dieases?
- Typhoid
- Dengue
- Pneumonia
- Malaria
The Correct Option is D
Approach Solution - 1
- Haemozoin is a toxic substance released during the breakdown of hemoglobin by the Plasmodium parasite, which causes malaria. This substance is responsible for the high fever and chills associated with malaria.
- In malaria, when the Plasmodium parasite infects red blood cells, it feeds on hemoglobin and releases haemozoin as a byproduct. This release causes an immune response that results in the fever and chills characteristic of the disease.
- Typhoid (Option A), dengue (Option B), and pneumonia (Option C) do not involve the production of haemozoin.
The correct answer is (D) : Malaria.
Approach Solution -2
The correct answer is: (D) Malaria.
Haemozoin is a toxic substance that is released by the *Plasmodium* parasite, which causes malaria. When the *Plasmodium* parasite infects red blood cells, it breaks down hemoglobin, releasing heme as a byproduct. The parasite then detoxifies the heme into haemozoin, which is stored within the parasite. This release of haemozoin into the bloodstream causes an inflammatory response, leading to high fever and chills, which are characteristic symptoms of malaria.
Malaria is transmitted to humans through the bite of an infected female Anopheles mosquito. The disease is characterized by recurrent fever episodes, anemia, and in severe cases, can lead to organ failure. The release of haemozoin plays a key role in the symptoms associated with malaria.
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