Question

The receptors for gamma amino butyric acid (GABA) in humans are

• A. ligand gated chloride ion channels
• B. ligand gated sodium ion channels
• C. ligand gated potassium ion channels
• D. ligand gated calcium ion channels

Hint:

Remember: GABA\(_A\) → chloride channel (fast inhibition); GABA\(_B\) → GPCR (slow inhibition).

Answer 1

The Correct Option is A

Step 1: Recall GABA receptor types.
- GABA\(_A\) receptors are ionotropic and function as ligand-gated chloride channels.
- GABA\(_B\) receptors are metabotropic (G-protein coupled).
Step 2: Function.
When GABA binds, chloride ions enter the neuron, hyperpolarizing the cell and inhibiting firing.
Step 3: Eliminate wrong options.
Sodium, potassium, and calcium ion channels are not the primary GABA receptor mechanism.
Final Answer: \[ \boxed{\text{GABA receptors are ligand-gated chloride ion channels.}} \]