Question:

The length of DNA helix in a typical nucleosome is

KCET - 2020
KCET

Updated On: Apr 9, 2025

200 bp
1000 bp
$3.2 \times 10^6 $ bp
$ 6.6 \times 10^9$ bp

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The Correct Option is A

Approach Solution - 1

A nucleosome is the basic structural unit of chromatin, consisting of DNA wrapped around histone proteins.

The length of DNA in a nucleosome is ~146 base pairs (bp) tightly bound to the histone core, with an additional ~54 bp as linker DNA, totaling ~200 bp per nucleosome.

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Approach Solution -2

Nucleosome core: ~146 bp wrapped around histone octamer.
Linker DNA: ~54 bp between nucleosomes.
Total: ~200 bp per nucleosome unit.

The correct answer is (A) 200 bp.

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