Histone H1, often referred to as the linker histone, binds to the DNA that enters and exits the nucleosome core particle, stabilizing the chromatin's higher-order structure. Unlike core histones (H2A, H2B, H3, H4), H1 is not part of the nucleosome octamer but instead associates with the linker DNA between nucleosomes, facilitating chromatin compaction.
| List I (Enzyme) | List II (Function) |
|---|---|
| (A) Cytochrome oxidase | (I) Electron transport system |
| (B) Topoisomerases | (II) Change linking number |
| (C) Cohesins | (III) DNA Replication |
| (D) PCNA | (IV) Cell cycle |
| List I | List II |
|---|---|
| (A) Histone erasers | (III) Deacetylases |
| (B) Histone readers | (IV) Bromodomain proteins |
| (C) Histone writers | (I) Methyltransferase |
| (D) DNA unwinding | (II) Topoisomerase |