Question

The following statement about Keloid is true:

• A. It contains growth factor
• B. Extended excision is the treatment of choice
• C. It does not extend beyond the wound
• D. None of the above

Hint:

Keloids overflow past the wound and recur after excision - their engine is excess growth factor.

Answer 1

The Correct Option is A

Step 1: A keloid is an abnormal scar produced by excessive deposition of collagen during wound healing. The dysregulated healing is driven by increased fibroblast activity and elevated growth factors, especially transforming growth factor beta (TGF-beta), so keloids do contain growth factor. Option (a) is true.
Step 2: The defining feature of a keloid is that it extends BEYOND the original wound margins, unlike a hypertrophic scar which stays within the wound. Therefore option (c), saying it does not extend beyond the wound, is false (that describes a hypertrophic scar).
Step 3: Surgical excision alone, including extended excision, is NOT the treatment of choice because keloids recur frequently and often worse after surgery. Management relies on intralesional steroids, pressure, silicone, and adjuncts; surgery is reserved and combined with adjuvant therapy. So option (b) is false.
Step 4: Since a correct statement (a) exists, option (d) None of the above is incorrect. The true statement is that a keloid contains growth factor.