Question:

The first step in glycolysis is:

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Step 1 "invests" energy—think of adding a phosphate as "locking the door" so the sugar can't leave the cell.
Updated On: May 5, 2026
  • Phosphorylation of glucose
  • Formation of fructose-6-phosphate
  • Formation of PGAL
  • Pyruvate formation
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The Correct Option is A

Solution and Explanation

Step 1: Concept
Glycolysis is the metabolic pathway that breaks down glucose into pyruvate to produce energy in the form of ATP.

Step 2: Meaning

Phosphorylation refers to the addition of a phosphate group to a molecule, typically utilizing ATP.

Step 3: Analysis

To begin the process and trap the glucose molecule inside the cell, an enzyme called hexokinase adds a phosphate group to the sixth carbon of glucose. This converts glucose into glucose-6-phosphate.

Step 4: Conclusion

Since the very first reaction involves the addition of a phosphate to glucose, the correct answer is phosphorylation of glucose. Final Answer: (A)
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