Question:
The final stage of peptidoglycan (PG) biosynthesis is marked by PG cross-link formation and remodeling. Which of the following enzymes does NOT take part in these processes?
The final stage of peptidoglycan (PG) biosynthesis is marked by PG cross-link formation and remodeling. Which of the following enzymes does NOT take part in these processes?
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Transpeptidases (penicillin-binding proteins) are key targets of β-lactam antibiotics.
Updated On: Sep 8, 2025
- Transglycosidases
- Transpeptidases
- Transaminases
- DD-carboxypeptidases
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The Correct Option is C
Solution and Explanation
Step 1: Recall peptidoglycan biosynthesis.
- Transglycosidases: Link glycan chains.
- Transpeptidases: Cross-link peptide chains.
- DD-carboxypeptidases: Modify cross-links in PG remodeling.
Step 2: Exclude non-participant.
Transaminases are involved in amino acid metabolism, not in PG cross-linking or remodeling.
Final Answer: \[ \boxed{\text{Transaminases do not participate in peptidoglycan biosynthesis.}} \]
- Transglycosidases: Link glycan chains.
- Transpeptidases: Cross-link peptide chains.
- DD-carboxypeptidases: Modify cross-links in PG remodeling.
Step 2: Exclude non-participant.
Transaminases are involved in amino acid metabolism, not in PG cross-linking or remodeling.
Final Answer: \[ \boxed{\text{Transaminases do not participate in peptidoglycan biosynthesis.}} \]
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