Question:

The condition resulting in Vitamin A deficiency that is irreversible is:

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"Xerosis" refers to dryness, whereas "-malacia" refers to softening or melting. Softening of the cornea is always a medical emergency and a sign of permanent damage.
Updated On: Jul 4, 2026
  • Xeropthalmia
  • Xerosis of conjunctiva
  • Phrynoderma
  • Keratomalacia
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The Correct Option is D

Solution and Explanation

Concept: Vitamin A deficiency affects the eyes in a progressive condition called Xerophthalmia.

• Early stages: Night blindness and dryness (reversible).

• Late stages: Structural damage to the cornea (irreversible).

Step 1: Analyzing early stages.
Xerosis of conjunctiva involves dryness of the white part of the eye. This can be cured by administering high doses of Vitamin A.

Step 2: Defining Keratomalacia.
This is the most severe stage of Vitamin A deficiency. It involves the liquefaction and melting of the cornea.

Step 3: Why it is irreversible.
Once the cornea collapses or is destroyed, the eye structure cannot be repaired by vitamins. It results in total and permanent blindness. Final Answer: (D)
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