The condition resulting in Vitamin A deficiency that is irreversible is:
Show Hint
"Xerosis" refers to dryness, whereas "-malacia" refers to softening or melting. Softening of the cornea is always a medical emergency and a sign of permanent damage.
Concept:
Vitamin A deficiency affects the eyes in a progressive condition called Xerophthalmia.
• Early stages: Night blindness and dryness (reversible).
• Late stages: Structural damage to the cornea (irreversible).
Step 1: Analyzing early stages.
Xerosis of conjunctiva involves dryness of the white part of the eye.
This can be cured by administering high doses of Vitamin A.
Step 2: Defining Keratomalacia.
This is the most severe stage of Vitamin A deficiency.
It involves the liquefaction and melting of the cornea.
Step 3: Why it is irreversible.
Once the cornea collapses or is destroyed, the eye structure cannot be repaired by vitamins.
It results in total and permanent blindness.
Final Answer: (D)