Step 1: Understanding the Concept:
The ozone layer in the stratosphere protects the Earth from harmful ultraviolet (UV) radiation from the sun.
Certain man-made chemicals can break down ozone molecules, leading to the thinning of this protective layer.
Step 2: Detailed Explanation:
Chlorofluorocarbons (CFCs) are highly stable compounds formerly used in refrigerants and aerosols.
When they reach the stratosphere, UV radiation breaks them down, releasing chlorine atoms.
A single chlorine atom can destroy thousands of ozone (O$_3$) molecules through a catalytic cycle.
While CO$_2$ is a greenhouse gas, DDT is a pesticide, and SO$_2$ causes acid rain, CFCs are the primary culprits for ozone depletion.
Step 3: Final Answer:
The correct option is (A).