Question:

Study the following and choose the correct statements:
• During muscle contraction, whenever action potential reaches the sarcoplasmic reticulum, \(Ca^{++}\) ions are released into the sarcoplasm.
• Accumulation of lactic acid in sarcoplasm leads to muscle fatigue.
• Ethmoid is considered as the keystone bone of the cranium.
• Sacrum is formed by the fusion of four sacral vertebrae.

Show Hint

Sphenoid = Keystone bone of skull Sacrum = Fusion of 5 sacral vertebrae Calcium release from SR initiates muscle contraction.
Updated On: Jun 17, 2026
  • I, III
  • II, IV
  • I, II
  • III, IV
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The Correct Option is C

Solution and Explanation

Concept: This question combines concepts from muscular physiology and skeletal system. Each statement should be examined independently.

Step 1:
Check Statement I. Action potential travels through T-tubules. This stimulates sarcoplasmic reticulum. Sarcoplasmic reticulum releases: \[ Ca^{++} \] into sarcoplasm. Calcium binds troponin and initiates contraction. Hence Statement I is correct.

Step 2:
Check Statement II. During vigorous exercise: \[ \text{Glucose} \rightarrow \text{Lactic Acid} \] Lactic acid accumulates in muscle fibers. This causes temporary muscle fatigue. Hence Statement II is correct.

Step 3:
Check Statement III. The keystone bone of cranium is: \[ \boxed{\text{Sphenoid bone}} \] not Ethmoid bone. Hence Statement III is incorrect.

Step 4:
Check Statement IV. Sacrum is formed by fusion of: \[ 5 \text{ sacral vertebrae} \] and not four. Therefore Statement IV is incorrect.

Step 5:
Select correct statements. Only Statements I and II are correct. \[ \boxed{\text{Option (C)}} \]
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