Question:

Study the following and choose the correct statements: I. If a single gene influences more than one phenotypic trait, it is called pleiotropy. II. Due to absence of antibodies anti A and anti B, the persons with AB blood group are described as universal recipients. III. Inheritance of sex-linked dominant traits follows criss-cross inheritance. IV. If sex index ratio is 0.33, then sexual phenotype of Drosophila is intersex.

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AB blood group = Universal recipient. Pleiotropy = One gene affects many traits.
Updated On: Jun 12, 2026
  • I, III
  • II, IV
  • III, IV
  • I, II
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The Correct Option is D

Solution and Explanation

Concept: This question combines concepts from genetics, blood groups, sex-linked inheritance, and sex determination in Drosophila.

Step 1:
Examine Statement I. Pleiotropy refers to a situation where a single gene controls multiple phenotypic traits. Example: Phenylketonuria affects several body systems. Therefore Statement I is correct.

Step 2:
Examine Statement II. AB blood group individuals possess both A and B antigens. They lack anti-A and anti-B antibodies. Hence they can receive blood from all ABO groups. Therefore Statement II is correct.

Step 3:
Examine Statement III. Criss-cross inheritance is a characteristic feature of X-linked recessive inheritance. The statement specifically mentions sex-linked dominant traits. Hence Statement III is considered incorrect.

Step 4:
Examine Statement IV. Sex index \[ =\frac{X}{A} \] For \[ 0.33 \] the phenotype is a metamale. Intersex occurs when ratio lies between 0.5 and 1. Thus Statement IV is incorrect.

Step 5:
Select the correct combination. Correct statements: \[ I,\ II \] Hence option (D).
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