Question:

SN2 reactions are favoured by:

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$S_{N}2$ loves "space" (Primary) and "free" nucleophiles (Aprotic solvents).
Updated On: May 5, 2026
  • Tertiary substrates
  • Polar protic solvents
  • Primary substrates and polar aprotic solvents
  • Secondary substrates and heat
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The Correct Option is C

Solution and Explanation

Step 1: Concept
$S_{N}2$ (Substitution Nucleophilic Bimolecular) reactions involve a single-step mechanism where the nucleophile attacks from the backside.

Step 2: Meaning

Because the attack happens simultaneously with the leaving group departing, steric hindrance must be minimized.

Step 3: Analysis

Primary substrates are least hindered, making them ideal for $S_{N}2$. Furthermore, polar aprotic solvents (like DMSO or acetone) do not solvate the nucleophile strongly, keeping it reactive.

Step 4: Conclusion

Tertiary substrates and polar protic solvents instead favor the $S_{N}1$ mechanism. Final Answer: (C)
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