Question:

Serpiginous ulcer in the distal esophagus is classically caused by-

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Which viral esophagitis gives winding serpentine ulcers in the lower esophagus that can merge into giant ulcers?
Updated On: Jun 23, 2026
  • CMV
  • Herpes
  • Pill
  • Corrosive
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The Correct Option is A

Solution and Explanation

Step 1: Infectious esophagitis produces characteristic ulcer patterns that help identify the organism on endoscopy.
Step 2: Cytomegalovirus (CMV) classically causes serpiginous (snake-like, winding) ulcers in the distal esophagus. These can coalesce to form large or giant ulcers.
Step 3: By contrast, herpes simplex virus typically produces small, shallow, well-circumscribed ulcers (volcano-like) often in the mid esophagus, pill esophagitis causes a localized ulcer at a point of pill lodgement, and corrosive injury causes diffuse circumferential burns rather than serpiginous ulcers.
Step 4: Because the described lesion is serpiginous and distal, the answer is CMV.
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