Question

Roth spots are seen in:

• A. Uveal melanoma
• B. Acute leukaemia
• C. Both a & b
• D. None of the above

Hint:

White-centred retinal hemorrhages classically tied to a blood malignancy.

Answer 1

The Correct Option is B

Step 1: Roth spots are retinal hemorrhages with white or pale centers. The pale center is made of coagulated fibrin with platelets, focal ischemia, inflammatory cells, infectious organisms, or neoplastic cells.
Step 2: They are seen in several systemic conditions: leukemia, subacute bacterial endocarditis, diabetes, pernicious anemia, hypertensive retinopathy, ischemic events, and rarely HIV retinopathy.
Step 3: Among the given options, acute leukaemia is the classic association, so option (b) is correct. Uveal melanoma is not a recognised cause of Roth spots, so option (a) and the combined option (c) are wrong.
Step 4: The answer is acute leukaemia, option (b).