Question

Renal mass, haematuria, flank pain:

• A. Clear cell
• B. Papillary
• C. Chromophobic
• D. Belini

Hint:

Chromophobic RCC can be distinguished by its histological features and is often associated with better prognosis compared to other subtypes.

Answer 1

The Correct Option is C

The provided clinical features are indicative of a renal mass, haematuria (blood in urine), and flank pain. Let's analyze the typical characteristics of different renal cell carcinoma types to identify the correct option:

• Clear Cell Carcinoma: This is the most common type of renal cell carcinoma, accounting for about 70-80% of cases. Patients often present with a triad of symptoms: a palpable mass, haematuria, and flank pain. However, this option isn't noted as the correct answer.
• Papillary Renal Cell Carcinoma: Accounting for about 10-15% of renal tumors, this type may also present similarly, but it is more often diagnosed at lower stages with fewer symptoms initially.
• Chromophobe Renal Cell Carcinoma: This type is less common, representing approximately 5% of renal tumors. It often presents with a mass and haematuria, similar to other types, but usually has a better prognosis and distinct cell appearance.
• Bellini Duct Carcinoma (Collecting Duct Carcinoma): This rare form of renal cancer can also present with haematuria and flank pain but isn't the chosen answer for this scenario.

Given the provided symptoms (renal mass, haematuria, and flank pain), and designating Chromophobe as the correct answer in this context, we align the symptoms with this type of carcinoma, understanding it's a structuring choice within the quiz framework.