Question:
Renal calculi associated with Proteus infection is:
Renal calculi associated with Proteus infection is:
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Urease-splitting organism alkalinises urine and precipitates struvite.
Updated On: Jun 24, 2026
- Uric acid
- Triple phosphate
- Calcium oxalate
- Xanthine
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The Correct Option is B
Solution and Explanation
Step 1: Link the organism to urine chemistry.
Proteus species are urease-producing bacteria. Urease splits urea into ammonia, which raises (alkalinises) the urine pH.
Step 2: Determine which stone forms in alkaline urine.
In alkaline, ammonia-rich urine, magnesium ammonium phosphate (struvite), also called triple phosphate, precipitates. These are the classic infection stones and form large staghorn calculi.
Step 3: Exclude the other stones.
Uric acid and xanthine stones form in acidic urine. Calcium oxalate, the most common stone overall, is metabolic and not driven by urease-producing infection.
Conclusion: Proteus produces triple phosphate (struvite) stones, matching the printed key.
Proteus species are urease-producing bacteria. Urease splits urea into ammonia, which raises (alkalinises) the urine pH.
Step 2: Determine which stone forms in alkaline urine.
In alkaline, ammonia-rich urine, magnesium ammonium phosphate (struvite), also called triple phosphate, precipitates. These are the classic infection stones and form large staghorn calculi.
Step 3: Exclude the other stones.
Uric acid and xanthine stones form in acidic urine. Calcium oxalate, the most common stone overall, is metabolic and not driven by urease-producing infection.
Conclusion: Proteus produces triple phosphate (struvite) stones, matching the printed key.
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