Question

Presence of which one of the following in the urine indicates pregnancy in human?

• A. Progesterone
• B. Follicle-stimulating hormone and luteinizing hormone
• C. Estrogen
• D. Human chorionic gonadotropin

Hint:

Urine pregnancy tests detect {hCG}, secreted by the trophoblast cells after fertilization and implantation — typically detectable within 10–14 days.

Answer 1

The Correct Option is D

Step 1: Recall the hormonal basis of pregnancy detection.
During early pregnancy, the placenta secretes human chorionic gonadotropin (hCG), a glycoprotein hormone that maintains the corpus luteum and progesterone secretion.
Step 2: Basis of urine pregnancy tests.
Pregnancy test kits detect hCG in urine using immunoassay techniques. The presence of hCG confirms implantation and placental activity.
Step 3: Eliminate incorrect options.
(A) Progesterone and (C) Estrogen are ovarian hormones, not diagnostic of pregnancy in urine.
(B) FSH and LH are pituitary hormones suppressed during pregnancy.

Step 4: Conclusion.
Thus, the presence of human chorionic gonadotropin (hCG) in urine indicates pregnancy.