Question:

Polysubstitution is a major drawback in:

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The alkyl group introduced in Friedel-Crafts alkylation activates the ring, making the product more reactive than the starting arene.
Updated On: Nov 5, 2026
  • Reimer Tiemann reaction
  • Friedel Craft's alkylation
  • Acetylation of aniline
  • Friedel Craft's acylation
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The Correct Option is B

Solution and Explanation

In Friedel-Crafts alkylation the new alkyl group is electron-donating (+I, hyperconjugation), so the mono-alkylated product is more reactive towards electrophiles than benzene itself.
Hence further alkylation occurs readily and a mixture of poly-alkylated products is obtained.
In Friedel-Crafts acylation the acyl group is electron-withdrawing and deactivates the ring, so polysubstitution does not occur.
Acetylation of aniline gives acetanilide (mono N-acylation), and the Reimer-Tiemann reaction gives mainly mono (ortho) formylation.
Answer: (2) Friedel Craft's alkylation
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