Question:
Paget's disease of this type is associated with cancer of which organ?
Paget's disease of this type is associated with cancer of which organ?
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Think of apocrine-bearing skin of the female genital tract.
Updated On: Jun 24, 2026
- Vulva
- Vagina
- Cervix
- Uterus
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The Correct Option is A
Solution and Explanation
Step 1: Extramammary Paget's disease (EMPD) is a rare, slow-growing intraepithelial adenocarcinoma that arises in skin bearing apocrine glands, outside the breast.
Step 2: In the female genital tract the classic site is the vulva, where it presents as a chronic eczematous, well-demarcated plaque and may be linked to an underlying adnexal or visceral adenocarcinoma.
Step 3: Therefore option A is correct. The vagina, cervix and uterus are lined by mucosa without the apocrine-rich skin in which Paget's disease typically develops.
Step 2: In the female genital tract the classic site is the vulva, where it presents as a chronic eczematous, well-demarcated plaque and may be linked to an underlying adnexal or visceral adenocarcinoma.
Step 3: Therefore option A is correct. The vagina, cervix and uterus are lined by mucosa without the apocrine-rich skin in which Paget's disease typically develops.
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