Question:
Mifepristone is used in?
Mifepristone is used in?
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An antiprogestin shrinks a progesterone-driven uterine tumour; methotrexate handles the tubal one.
Updated On: Jun 24, 2026
- Molar pregnancy
- Threatened abortion
- Fibroid
- Ectopic pregnancy
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The Correct Option is C
Solution and Explanation
Step 1: Identify the drug. Mifepristone is a progesterone receptor antagonist (antiprogestin) and also has antiglucocorticoid activity.
Step 2: Recall its uses. It is best known for medical termination of pregnancy with misoprostol, for emergency contraception, and notably for the medical management of uterine fibroids (leiomyoma), where blocking progesterone shrinks the fibroid and reduces bleeding.
Step 3: Eliminate harmful or non-indicated options. In threatened abortion (option B) progesterone support is desired, so an antiprogestin is contraindicated. In molar pregnancy (A) the management is evacuation, not mifepristone.
Step 4: Address ectopic pregnancy. The standard medical agent for ectopic pregnancy is methotrexate, not mifepristone; mifepristone is not an accepted treatment for it. So option D is not correct.
Step 5: Choose the best answer. Among the listed options, fibroid is the recognised indication for mifepristone.
Answer: Option C, Fibroid. (The printed key lists C over D; the medically correct single answer is fibroid, since methotrexate, not mifepristone, manages ectopic pregnancy.)
Step 2: Recall its uses. It is best known for medical termination of pregnancy with misoprostol, for emergency contraception, and notably for the medical management of uterine fibroids (leiomyoma), where blocking progesterone shrinks the fibroid and reduces bleeding.
Step 3: Eliminate harmful or non-indicated options. In threatened abortion (option B) progesterone support is desired, so an antiprogestin is contraindicated. In molar pregnancy (A) the management is evacuation, not mifepristone.
Step 4: Address ectopic pregnancy. The standard medical agent for ectopic pregnancy is methotrexate, not mifepristone; mifepristone is not an accepted treatment for it. So option D is not correct.
Step 5: Choose the best answer. Among the listed options, fibroid is the recognised indication for mifepristone.
Answer: Option C, Fibroid. (The printed key lists C over D; the medically correct single answer is fibroid, since methotrexate, not mifepristone, manages ectopic pregnancy.)
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