Question

Match the following :

Column I		Column II
i.	Cyclosporin - A	a.	Clot busters
ii.	Streptokinase	b.	Antibiotic
iii.	Statins	c.	Immuno supressive agent
iv.	Penicillin	d.	Blood cholesterol lowering agent

• A. i-c, ii-a, iii-d, iv-b
• B. i-c, ii-d, iii-a, iv-b
• C. i-a, ii-b, iii-c, iv-d
• D. i-a, ii-b, iii-d, iv-c

Answer 1

The Correct Option is A

Let's match each item in Column I with its corresponding description or function in Column II:

• i. Cyclosporin - A: This is a bioactive molecule produced by the fungus Tolypocladium inflatum. It is widely used as an immunosuppressive agent (c), particularly in organ transplant patients to prevent graft rejection.  
  So, i → c.
• ii. Streptokinase: This enzyme is produced by the bacterium Streptococcus. It is used medically as a thrombolytic agent, meaning it helps dissolve blood clots. It acts as a clot buster (a), used to treat conditions like myocardial infarction (heart attack). 
  So, ii → a.
• iii. Statins: These compounds, originally isolated from fungi like Monascus purpureus (yeast) and Aspergillus terreus, competitively inhibit the enzyme responsible for cholesterol synthesis (HMG-CoA reductase). They are used as blood cholesterol lowering agents (d). 
  So, iii → d.
• iv. Penicillin: Discovered by Alexander Fleming from the fungus Penicillium notatum, penicillin was the first widely used antibiotic (b), effective against many bacterial infections. 
  So, iv → b.

The correct matching sequence is:

• i → c
• ii → a
• iii → d
• iv → b

Comparing this to the options provided:

• i-c, ii-a, iii-d, iv-b
• i-c, ii-d, iii-a, iv-b
• i-a, ii-b, iii-c, iv-d
• i-a, ii-b, iii-d, iv-c

The correct option is i-c, ii-a, iii-d, iv-b.

Answer 2

Here’s the correct matching of the substances in Column I with their corresponding properties in Column II:

Cyclosporin-A: This is an immunosuppressive agent used to prevent organ transplant rejection.

• Corresponding property: c. Immunosuppressive agent

Streptokinase: This is used as a clot buster to break down clots in blood vessels.

• Corresponding property: a. Clot busters

Statins: These are drugs used to lower blood cholesterol levels.

• Corresponding property: d. Blood cholesterol lowering agent

Penicillin: This is an antibiotic used to treat bacterial infections.

• Corresponding property: b. Antibiotic

Thus, the correct option is:

The correct answer is (A) : i-c, ii-a, iii-d, iv-b.