Concept:
Many endocrine disorders arise due to deficiency or excess secretion of hormones. Matching hormones with their associated disorders is a very important topic in Human Physiology.
Step 1: Match Growth Hormone with its disorder.
Growth hormone is secreted by the anterior pituitary gland.
Deficiency of growth hormone during childhood causes:
\[
\boxed{\text{Dwarfism}}
\]
Therefore,
\[
A \rightarrow IV
\]
Step 2: Match Thyroxine with its disorder.
Thyroxine is secreted by the thyroid gland.
Deficiency of thyroxine during infancy results in:
\[
\boxed{\text{Cretinism}}
\]
Characteristics include:
• Stunted growth
• Mental retardation
• Delayed development
Therefore,
\[
B \rightarrow III
\]
Step 3: Match Cortisol with its disorder.
Cortisol is secreted by adrenal cortex.
Deficiency of adrenal cortical hormones produces:
\[
\boxed{\text{Addison's disease}}
\]
Symptoms include:
• Fatigue
• Weight loss
• Low blood pressure
Therefore,
\[
C \rightarrow I
\]
Step 4: Match Insulin with its disorder.
Insulin is secreted by β-cells of pancreas.
Insufficient insulin causes:
\[
\boxed{\text{Diabetes mellitus}}
\]
Characterized by:
• Hyperglycemia
• Glucose in urine
• Excessive thirst
Therefore,
\[
D \rightarrow II
\]
Step 5: Write the final matching.
\[
A-IV,\; B-III,\; C-I,\; D-II
\]
Hence,
\[
\boxed{\text{Option (B)}}
\]