Question

Match the following:

• A. (A)-(R), (B)-(P), (C)-(S), (D)-(Q)
• B. (A)-(P), (B)-(R), (C)-(Q), (D)-(S)
• C. (A)-(R), (B)-(Q), (C)-(P), (D)-(S)
• D. (A)-(S), (B)-(P), (C)-(R), (D)-(Q)

Answer 1

The Correct Option is A

Step 1: Understanding the concept of vitamin deficiency diseases.
Each disease listed in Column I is directly associated with the deficiency of a particular vitamin. Vitamins are essential micronutrients required for normal physiological functions. A deficiency disrupts specific biochemical pathways, leading to characteristic symptoms and diseases.
Step 2: Analysis of each disease in Column I.
(A) Scurvy:
Scurvy is caused by deficiency of Vitamin C (Ascorbic acid). Vitamin C is essential for collagen synthesis, which maintains the integrity of connective tissues. Its deficiency leads to bleeding gums, weak blood vessels, delayed wound healing, and fatigue. Hence, Scurvy is matched with Ascorbic acid (R).
(B) Convulsions:
Convulsions are often associated with deficiency of Vitamin B\(_6\) (Pyridoxine). Pyridoxine plays a crucial role in amino acid metabolism and neurotransmitter synthesis (such as GABA). Its deficiency affects the nervous system, leading to seizures or convulsions. Thus, Convulsions match with Pyridoxine (P).
(C) Cheilosis:
Cheilosis is characterized by cracks and sores at the corners of the mouth. It is caused by deficiency of Vitamin B\(_2\) (Riboflavin). Riboflavin is important for energy metabolism and maintaining healthy skin and mucous membranes. Therefore, Cheilosis corresponds to Riboflavin (S).
(D) Xerophthalmia:
Xerophthalmia is a condition involving dryness of the eyes and can lead to night blindness. It is caused by deficiency of Vitamin A, which is essential for vision (formation of rhodopsin in the retina) and maintenance of epithelial tissues. Hence, Xerophthalmia matches with Vitamin A (Q).
Step 3: Writing the correct matching.
\[ (A)-(R), \quad (B)-(P), \quad (C)-(S), \quad (D)-(Q) \] Step 4: Verification with given options.
Comparing the above matching with the provided options, we find that it exactly corresponds to option (A). All other options have incorrect pairings.
Step 5: Final conclusion.
Thus, by analyzing each disease and its associated vitamin deficiency, the correct matching is option (A).
Final Answer:} (A)