Question

Match List I with List II :

List I                  List II
A. Tetany               I. Inflammation of joints
B. Arthritis            II. Autoimmune disorder affecting neuromuscular junction
C. Myasthenia gravis    III. Wild contraction in muscle due to low Ca++ in body fluid
D. Muscular dystrophy   IV. Progressive degeneration of skeletal muscle

• A. A-IV, B-III, C-II, D-I
• B. A-III, B-I, C-II, D-IV
• C. A-I, B-II, C-III, D-IV
• D. A-III, B-II, C-I, D-IV

Hint:

Logic Tip: Pay attention to keywords. "Myasthenia" means muscle weakness, linked to the "Neuromuscular junction". "Dystrophy" indicates a genetic "Degeneration". "Tetany" sounds like tetanus, involving "Wild contractions".

Answer 1

The Correct Option is B

Concept:
Disorders of the muscular and skeletal systems can arise from genetic defects, autoimmune responses, nutritional deficiencies, or age-related wear and tear. Recognizing the hallmark symptoms of each condition is key.
Step 1:
Tetany is a medical sign characterized by rapid, wild spasms or sustained contractions in muscles. It is directly caused by hypocalcemia, which is a critically low level of calcium ions ($Ca^{++}$) in the body fluid. Match: A $\rightarrow$ III
Step 2:
The suffix "-itis" indicates inflammation. Arthritis is a broad term encompassing conditions that cause inflammation, pain, and stiffness in the joints. Match: B $\rightarrow$ I
Step 3:
Myasthenia gravis is an autoimmune disorder where the body's immune system erroneously attacks acetylcholine receptors at the neuromuscular junction. This disrupts nerve-muscle communication, leading to fatigue, weakening, and paralysis of skeletal muscle. Match: C $\rightarrow$ II
Step 4:
Muscular dystrophy refers to a group of genetic diseases (mostly X-linked recessive) that cause progressive weakness and degeneration of skeletal muscle mass over time due to the absence or defect of the structural protein dystrophin. Match: D $\rightarrow$ IV
Step 5:
Combining the matches yields A-III, B-I, C-II, D-IV, which perfectly aligns with Option (2).