Question:

Lithium causes which of the following electrolyte or metabolic effects?

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Recall the lithium ECG change and the electrolyte pattern it mimics.
Updated On: Jun 23, 2026
  • Hypokalemia
  • Hyperkalemia
  • Hypocalcemia
  • Hypercalcemia
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The Correct Option is A

Solution and Explanation

Step 1: Lithium has wide-ranging side effects across neurological, renal, cardiac, endocrine and GI systems.
Step 2: On the cardiovascular side, the effects of lithium resemble those of hypokalemia, and the most common ECG change is T wave depression or flattening.
Step 3: Among the listed options, the classically tested electrolyte association is that lithium produces hypokalemia-like cardiac effects.
Conclusion: The answer is hypokalemia.
Ref: KD Tripathi, Essentials of Medical Pharmacology.
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