Question

Increased chylomicron, lipemic serum is seen in:

• A. Lipoprotein lipase deficiency
• B. Hypercholesterolemia
• C. Familial hyperlipidemia
• D. Hypertriglyceridemia

Hint:

Lipoprotein lipase deficiency results in the accumulation of chylomicrons, leading to lipemic serum and increased triglycerides in the blood.

Answer 1

The Correct Option is A

The presence of increased chylomicrons and lipemic serum is indicative of a condition affecting lipid metabolism. In the context of the given options, we aim to identify which condition aligns with these symptoms.

Explanation:

1. Lipoprotein lipase deficiency: This condition is characterized by the inability of the enzyme lipoprotein lipase to properly break down triglycerides in the blood. This results in the accumulation of chylomicrons, leading to a lipemic, or milky, appearance of serum.
2. Hypercholesterolemia: Primarily involves elevated cholesterol levels and not triglycerides or chylomicrons.
3. Familial hyperlipidemia: This is a broader category and may involve various lipoprotein disorders, but not specifically increased chylomicrons.
4. Hypertriglyceridemia: Involves elevated triglyceride levels, but not necessarily due to increased chylomicrons.

Given the distinct symptoms of increased chylomicrons and lipemic serum, the most direct association is with lipoprotein lipase deficiency.

Conclusion: The correct answer is Lipoprotein lipase deficiency.