Question:
In ACLS, which drug can be given for ventricular fibrillation after cardiac arrest, other than epinephrine?
In ACLS, which drug can be given for ventricular fibrillation after cardiac arrest, other than epinephrine?
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For a shockable rhythm that resists defibrillation, the antiarrhythmic of choice is amiodarone.
Updated On: Jun 23, 2026
- Amiodarone
- Dopamine
- Adenosine
- Atropine
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The Correct Option is A
Solution and Explanation
Step 1: Ventricular fibrillation is a shockable rhythm. The core ACLS treatment is high-quality CPR and defibrillation, with drugs given to support the rhythm. Step 2: Epinephrine 1 mg of 1:10,000 is given every 3 to 5 minutes. When VF or pulseless VT persists despite shocks, an antiarrhythmic is added, and amiodarone (300 mg first dose, 150 mg second dose) is the recommended agent (lidocaine is the alternative). Step 3: Dopamine (option b) is a vasopressor for hypotension and bradycardia, not for VF. Adenosine (option c) is for stable narrow-complex SVT, not VF. Atropine (option d) is used for symptomatic bradycardia and has no role in VF. Step 4: Therefore, besides epinephrine, the drug given in VF is amiodarone (option a).
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