Concept:
When values of first and second derivatives are required at a specific point, it is often convenient to first simplify the function and then differentiate term by term.
The exponential function satisfies
\[
\frac{d}{dx}(e^{ax})=ae^{ax}.
\]
Step 1: Expand the given expression.
Given
\[
y=(e^{2x}-4)(6e^{2x}-5e^x+1).
\]
Multiplying,
\[
y=6e^{4x}-5e^{3x}+e^{2x}-24e^{2x}+20e^x-4.
\]
Therefore,
\[
y=6e^{4x}-5e^{3x}-23e^{2x}+20e^x-4.
\]
Step 2: Find the first derivative.
Differentiating term by term,
\[
\frac{dy}{dx}
=
24e^{4x}
-15e^{3x}
-46e^{2x}
+20e^x.
\]
Putting \(x=0\),
\[
\left(\frac{dy}{dx}\right)_{x=0}
=
24-15-46+20.
\]
\[
=
-17.
\]
Step 3: Find the second derivative.
Differentiating again,
\[
\frac{d^2y}{dx^2}
=
96e^{4x}
-45e^{3x}
-92e^{2x}
+20e^x.
\]
At \(x=0\),
\[
\left(\frac{d^2y}{dx^2}\right)_{x=0}
=
96-45-92+20.
\]
\[
=-21.
\]
Step 4: Calculate the required quantity.
\[
\left(\frac{dy}{dx}\right)_{x=0}
-
\left(\frac{d^2y}{dx^2}\right)_{x=0}
\]
\[
=
(-17)-(-21).
\]
\[
=4.
\]
Hence
\[
\boxed{4}.
\]