Concept:
A partial derivative measures the rate of change of a multivariable function with respect to one variable while treating all the remaining variables as constants.
For an exponential function,
\[
\frac{\partial}{\partial z}\left(e^{u}\right)
=
e^{u}\cdot\frac{\partial u}{\partial z},
\]
which follows from the chain rule.
Also,
\[
\frac{\partial}{\partial z}\left(x^2\right)=0,\qquad
\frac{\partial}{\partial z}\left(\cos4w\right)=0,
\]
since \(x\) and \(w\) are treated as constants while differentiating with respect to \(z\).
Hence, only the exponential term contributes to the derivative.
Step 1: Write the given function.
The given function is
\[
f(x,y,z,w)
=
x^{2}e^{2y+3z}\cos(4w).
\]
We have to calculate
\[
\frac{\partial f}{\partial z}.
\]
Step 2: Differentiate with respect to \(z\).
Since \(x^2\) and \(\cos(4w)\) are constants with respect to \(z\),
\[
\frac{\partial f}{\partial z}
=
x^{2}\cos(4w)
\cdot
\frac{\partial}{\partial z}
\left(e^{2y+3z}\right).
\]
Applying the chain rule,
\[
\frac{\partial}{\partial z}
\left(e^{2y+3z}\right)
=
e^{2y+3z}\cdot
\frac{\partial}{\partial z}(2y+3z).
\]
Since
\[
\frac{\partial}{\partial z}(2y+3z)=3,
\]
therefore,
\[
\frac{\partial}{\partial z}
\left(e^{2y+3z}\right)
=
3e^{2y+3z}.
\]
Hence,
\[
\boxed{
\frac{\partial f}{\partial z}
=
3x^{2}e^{2y+3z}\cos(4w)
}.
\]
Step 3: Substitute the given point \((2,0,-2,1)\).
Substituting,
\[
x=2,\qquad
y=0,\qquad
z=-2,\qquad
w=1.
\]
Therefore,
\[
\frac{\partial f}{\partial z}
=
3(2)^2
e^{2(0)+3(-2)}
\cos(4).
\]
Step 4: Simplify the expression.
First,
\[
(2)^2=4.
\]
Also,
\[
2(0)+3(-2)
=
-6.
\]
Hence,
\[
\frac{\partial f}{\partial z}
=
3\times4\times e^{-6}\cos4.
\]
Therefore,
\[
=
12e^{-6}\cos4.
\]
Since
\[
e^{-6}=\frac1{e^6},
\]
we obtain
\[
\boxed{
\frac{\partial f}{\partial z}
=
\frac{12\cos4}{e^6}
}.
\]
Step 5: Compare with the given options.
The obtained result is
\[
\frac{12\cos4}{e^6},
\]
which exactly matches
\[
\boxed{\text{Option (B)}}.
\]
Hence,
\[
\boxed{\text{Correct Answer = (2)}}
\]
Step 6: Alternative shortcut.
Instead of differentiating the entire function,
remember that
\[
\frac{\partial}{\partial z}
\left(e^{2y+3z}\right)
=
3e^{2y+3z}.
\]
Thus,
\[
\frac{\partial f}{\partial z}
=
3f(x,y,z,w).
\]
Now simply evaluate
\[
f(2,0,-2,1)
=
4e^{-6}\cos4.
\]
Therefore,
\[
\frac{\partial f}{\partial z}
=
3\left(4e^{-6}\cos4\right)
=
\frac{12\cos4}{e^6}.
\]
This shortcut is very useful in objective examinations.