Identify the incorrect statement about tertiary structure of proteins.
- They can be fibrous or globular in structure
- The main forces that stabilize the structure are hydrogen bonding, disulphide links, van der Waals and electrostatic forces of attraction
- The structure remains intact when exposed to pH changes
- A linear polypeptide chain will convert to a secondary structure and then further folding of the secondary structure will convert to tertiary structure
The Correct Option is C
Solution and Explanation
Tertiary structure refers to the overall folding of the polypeptide chain. It is highly sensitive to the surrounding environment.
Step 2: Detailed Explanation:
Option A: True. Tertiary structure describes the 3D shape, which is often globular or fibrous.
Option B: True. These are the various intermolecular and intramolecular forces that hold the 3D shape together.
Option C: Incorrect. Proteins undergo denaturation when exposed to significant changes in pH or temperature. This process disrupts the tertiary and secondary structures.
Option D: True. Protein folding follows a hierarchical path from primary to secondary to tertiary.
Step 3: Final Answer:
Statement (C) is incorrect.
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