Question:
Gastrin is a hormone secreted by gastrointestinal (GI) tract, which stimulates the secretion of
Gastrin is a hormone secreted by gastrointestinal (GI) tract, which stimulates the secretion of
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Etymology helps: "Gastrin" relates to "gastric" (stomach). Therefore, it naturally stimulates stomach secretions (HCl and pepsinogen).
Updated On: Apr 28, 2026
- Hydrochloric acid and pepsinogen
- Pancreatic enzymes and bile juice
- Water and bicarbonate ions
- Bicarbonate ions and pepsinogen
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept: The gastrointestinal tract secretes several local hormones (like gastrin, secretin, CCK) that regulate the release of digestive juices.
Step 2: Key Formula or Approach: Match the origin of the hormone to its specific target organ and subsequent physiological secretion.
Step 3: Detailed Explanation: Gastrin is produced by the G-cells located in the pyloric region of the stomach mucosa.
It acts locally on the gastric glands and stimulates them to secrete gastric juice.
The two main components of gastric juice stimulated by gastrin are Hydrochloric acid (HCl), secreted from parietal (oxyntic) cells, and the proenzyme pepsinogen, secreted from chief (peptic) cells.
Secretin and CCK are the hormones responsible for stimulating pancreatic enzymes, bile juice, and bicarbonate ions.
Step 4: Final Answer: Gastrin stimulates the secretion of Hydrochloric acid and pepsinogen.
Step 2: Key Formula or Approach: Match the origin of the hormone to its specific target organ and subsequent physiological secretion.
Step 3: Detailed Explanation: Gastrin is produced by the G-cells located in the pyloric region of the stomach mucosa.
It acts locally on the gastric glands and stimulates them to secrete gastric juice.
The two main components of gastric juice stimulated by gastrin are Hydrochloric acid (HCl), secreted from parietal (oxyntic) cells, and the proenzyme pepsinogen, secreted from chief (peptic) cells.
Secretin and CCK are the hormones responsible for stimulating pancreatic enzymes, bile juice, and bicarbonate ions.
Step 4: Final Answer: Gastrin stimulates the secretion of Hydrochloric acid and pepsinogen.
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