Step 1: Analyze the inequality.
We are given:
\[
x<y<x+y
\]
From $y<x+y$, we conclude that $y>0$.
Thus, $y$ is always positive, and $x$ may be either negative or positive, but smaller than $y$.
Step 2: Check each option.
- (A) $-2x$: If $x<0$, then $-2x>0$ (positive). If $x>0$, then $-2x<0$ (negative). Therefore, this is not always negative.
- (B) $-y$: Since $y>0$, then $-y<0$. This is always negative.
- (C) $x-y$: Since $x<y$, subtracting gives $x-y<0$. This is always negative.
- (D) $2x-y$: Consider $x=5$, $y=6$. Then $2x-y = 10-6=4>0$, not always negative.
- (E) $3x$: If $x<0$, then $3x<0$. If $x>0$, then $3x>0$. So not always negative.
Step 3: Conclude the must-be-negative expressions.
The only expressions guaranteed to be negative under the given condition are:
\[
-y \quad \text{and} \quad x-y
\]
Final Answer:
\[
\boxed{-y \text{ and } x-y}
\]