Question:

Expressed Sequence Tags (ESTs) refers to:

Updated On: Apr 25, 2026
  • Genes expressed as RNA
  • Polypeptide expression
  • DNA polymorphism
  • Novel DNA sequences
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The Correct Option is A

Solution and Explanation

Expressed Sequence Tags (ESTs) are a significant component in the study of gene expression and are particularly relevant in genomic research. Let us explore the concept to identify the correct choice from the provided options.

Explanation:

  1. What are ESTs?

    Expressed Sequence Tags (ESTs) are short sub-sequences of cDNA (complementary DNA) sequences. They are derived from mRNA (messenger RNA) and represent the portions of a gene that are expressed as RNA.

  2. Role of ESTs:

    ESTs serve as a marker for gene expression studies. They help in identifying gene transcripts and are used to determine gene activity levels in different tissues. This provides insight into functional genomics and gene mapping.

  3. Analyzing the Options:
    • Genes expressed as RNA - This correctly defines ESTs as they are derived from mRNA, which represents genes expressed as RNA.
    • Polypeptide expression - This describes protein synthesis, not directly related to ESTs, which are about nucleic acids.
    • DNA polymorphism - This refers to variations in DNA sequences among individuals and is not specifically related to ESTs.
    • Novel DNA sequences - This is a broader term that could include new sequences but doesn't specifically relate to the expression of genes as RNA.
  4. Conclusion:

    Based on the explanation, the correct option is Genes expressed as RNA, as it directly correlates with the nature and purpose of ESTs.

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