Question:
Enzymes that utilize ATP in phosphate transfer require an alkaline earth metal (M) as the cofactor. M is:
Enzymes that utilize ATP in phosphate transfer require an alkaline earth metal (M) as the cofactor. M is:
Updated On: Apr 25, 2026
- Be
- Mg
- Ca
- Sr
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The Correct Option is B
Solution and Explanation
To solve this question, we need to understand the role of alkaline earth metals in enzyme activity, specifically those enzymes that utilize ATP for phosphate transfer. ATP, or adenosine triphosphate, is a molecule used by cells as a coenzyme to transfer energy for various metabolic processes, and it often requires a metal ion as a cofactor to assist in this function.
- Enzymes catalyzing reactions involving the transfer of a phosphate group from ATP generally require a divalent cation as a cofactor.
- Amongst the alkaline earth metals (group 2 of the periodic table), the most common ion used in biological systems for this purpose is magnesium (Mg2+).
- Magnesium ions stabilize the negative charges on the phosphate groups of ATP, facilitating the transfer of the phosphate group during enzymatic reactions.
- Other alkaline earth metals, such as calcium (Ca), strontium (Sr), and beryllium (Be), do not commonly serve this biological function due to their different chemical properties or biological availability compared to magnesium.
- Hence, the correct answer is Mg, as it is the alkaline earth metal required by enzymes that utilize ATP in phosphate transfer.
Conclusion: Option Mg is the correct choice because magnesium ions play a crucial role in ATP-dependent enzymatic reactions by stabilizing the structure of ATP and aiding in the transfer process.
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