Question:
Drug of choice in obsessive compulsive neurosis is
Drug of choice in obsessive compulsive neurosis is
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Think of the tricyclic antidepressant known for its strong serotonergic effect.
Updated On: Jul 16, 2026
- Clomipramine
- Haloperidol
- Clonazepam
- Carbamazepine
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Question:
The question asks for the classic drug of choice in obsessive-compulsive neurosis, that is, obsessive-compulsive disorder.
Step 2: Key Concept or Approach:
OCD responds to drugs that strongly boost serotonin transmission. The tricyclic antidepressant with the most potent serotonergic action, clomipramine, was the original benchmark drug for the condition before SSRIs became the everyday first choice, and it remains the classic answer in exams.
Step 3: Working Through the Options:
Clomipramine is a strongly serotonergic tricyclic antidepressant and is the traditional drug of choice for OCD. Haloperidol is an antipsychotic used for schizophrenia and acute psychosis, not for OCD, though it is sometimes added in resistant tic-related OCD, never as first-line therapy. Clonazepam is a benzodiazepine that can ease anxiety accompanying OCD but does not treat the obsessions and compulsions themselves. Carbamazepine is an anticonvulsant and mood stabiliser used in epilepsy and bipolar disorder, with no established role in OCD.
Step 4: Conclusion:
The correct answer is Clomipramine.
The question asks for the classic drug of choice in obsessive-compulsive neurosis, that is, obsessive-compulsive disorder.
Step 2: Key Concept or Approach:
OCD responds to drugs that strongly boost serotonin transmission. The tricyclic antidepressant with the most potent serotonergic action, clomipramine, was the original benchmark drug for the condition before SSRIs became the everyday first choice, and it remains the classic answer in exams.
Step 3: Working Through the Options:
Clomipramine is a strongly serotonergic tricyclic antidepressant and is the traditional drug of choice for OCD. Haloperidol is an antipsychotic used for schizophrenia and acute psychosis, not for OCD, though it is sometimes added in resistant tic-related OCD, never as first-line therapy. Clonazepam is a benzodiazepine that can ease anxiety accompanying OCD but does not treat the obsessions and compulsions themselves. Carbamazepine is an anticonvulsant and mood stabiliser used in epilepsy and bipolar disorder, with no established role in OCD.
Step 4: Conclusion:
The correct answer is Clomipramine.
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