Question:
Deficiency of Niacin is characterised by:
Deficiency of Niacin is characterised by:
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To prevent Pellagra, corn should be treated with lime (calcium hydroxide). This process, called nixtamalization, releases bound niacin, making it absorbable.
Updated On: Jul 4, 2026
- 2Ds Dementias & Dermatitis
- 3Ds Dermatitis, Diarrhoea & Dementia
- 4Ds Dermatitis, Dyspepsia, Dementia & Diarrhoea
- 5Ds Diarrhoea, Dermatitis, Dyslexia, Dyspepsia & Dementias
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The Correct Option is B
Solution and Explanation
Concept:
Niacin (Vitamin B3) is crucial for energy metabolism. Its severe deficiency leads to a disease called Pellagra.
• Pellagra was historically common in populations dependent on corn (maize) as a staple.
• The symptoms follow a distinct clinical pattern known as the "Ds."
Step 1: Identifying the primary symptoms.
The three classic clinical manifestations are skin issues, digestive issues, and mental issues.
Step 2: Defining the 3Ds.
1. Dermatitis: Scaly, dark skin rashes on areas exposed to sunlight. 2. Diarrhoea: Significant gastrointestinal distress. 3. Dementia: Mental confusion, memory loss, and disorientation.
Step 3: The fourth D.
If left untreated, Pellagra leads to a fourth "D"—Death. However, the standard diagnostic characterization uses the 3Ds. Final Answer: (B)
• Pellagra was historically common in populations dependent on corn (maize) as a staple.
• The symptoms follow a distinct clinical pattern known as the "Ds."
Step 1: Identifying the primary symptoms.
The three classic clinical manifestations are skin issues, digestive issues, and mental issues.
Step 2: Defining the 3Ds.
1. Dermatitis: Scaly, dark skin rashes on areas exposed to sunlight. 2. Diarrhoea: Significant gastrointestinal distress. 3. Dementia: Mental confusion, memory loss, and disorientation.
Step 3: The fourth D.
If left untreated, Pellagra leads to a fourth "D"—Death. However, the standard diagnostic characterization uses the 3Ds. Final Answer: (B)
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