Question:
Choose the mismatched pair:
Choose the mismatched pair:
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Polio vaccines are OPV (live attenuated) and IPV (inactivated), not recombinant vector vaccines.
Updated On: Jun 12, 2026
- Attenuated whole agent vaccines — Hepatitis A vaccine
- Inactivated whole agent vaccines — Cholera vaccine
- Toxoids — Diphtheria vaccine
- Recombinant vector vaccines — Polio vaccine
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The Correct Option is D
Solution and Explanation
Concept:
Vaccines are prepared using different biological approaches. Classification depends on how the antigen is produced and introduced into the body.
Step 1: Analyze the attenuated vaccine pair. Attenuated vaccines contain weakened forms of pathogens capable of stimulating immunity without causing severe disease. The given pair is accepted as correctly matched.
Step 2: Analyze the inactivated vaccine pair. Cholera vaccines are examples of inactivated whole-agent vaccines. Thus this pair is correctly matched.
Step 3: Analyze the toxoid vaccine pair. Diphtheria vaccine contains diphtheria toxoid. A toxoid is an inactivated bacterial toxin that still retains antigenicity. Therefore this pair is correct.
Step 4: Examine the recombinant vector vaccine pair. Polio vaccines are traditionally of two types: \[ \text{OPV (Oral Polio Vaccine)} \] and \[ \text{IPV (Inactivated Polio Vaccine)} \] Neither is classified as a recombinant vector vaccine. Therefore this pairing is incorrect.
Step 5: State the answer. The mismatched pair is \[ \boxed{\text{Recombinant vector vaccines — Polio vaccine}} \]
Step 1: Analyze the attenuated vaccine pair. Attenuated vaccines contain weakened forms of pathogens capable of stimulating immunity without causing severe disease. The given pair is accepted as correctly matched.
Step 2: Analyze the inactivated vaccine pair. Cholera vaccines are examples of inactivated whole-agent vaccines. Thus this pair is correctly matched.
Step 3: Analyze the toxoid vaccine pair. Diphtheria vaccine contains diphtheria toxoid. A toxoid is an inactivated bacterial toxin that still retains antigenicity. Therefore this pair is correct.
Step 4: Examine the recombinant vector vaccine pair. Polio vaccines are traditionally of two types: \[ \text{OPV (Oral Polio Vaccine)} \] and \[ \text{IPV (Inactivated Polio Vaccine)} \] Neither is classified as a recombinant vector vaccine. Therefore this pairing is incorrect.
Step 5: State the answer. The mismatched pair is \[ \boxed{\text{Recombinant vector vaccines — Polio vaccine}} \]
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