Question:
Caffeine is a plant-based drug that
Caffeine is a plant-based drug that
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Caffeine’s effect on increasing cAMP is a key reason for its stimulating properties in the central nervous system.
Updated On: Dec 11, 2025
- does not intercalate into DNA double helix
- inhibits cyclic AMP (cAMP) phosphodiesterase activity
- inhibits epinephrine response
- reduces the level of cellular cAMP
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The Correct Option is B
Solution and Explanation
Step 1: Understanding Caffeine's Action.
Caffeine works by inhibiting the activity of phosphodiesterase, an enzyme responsible for breaking down cyclic AMP (cAMP). This increases the concentration of cAMP in cells.
Step 2: Analyzing the Options.
- (A) Incorrect. Caffeine does not intercalate into DNA; it mainly affects cellular signaling pathways.
- (B) Correct. Caffeine inhibits the phosphodiesterase enzyme, increasing cAMP levels.
- (C) Incorrect. Caffeine does not directly inhibit the epinephrine response; instead, it stimulates it by increasing cAMP levels.
- (D) Incorrect. Caffeine increases, not reduces, the level of cAMP by inhibiting its breakdown.
Step 3: Conclusion.
Thus, the correct answer is (B).
Caffeine works by inhibiting the activity of phosphodiesterase, an enzyme responsible for breaking down cyclic AMP (cAMP). This increases the concentration of cAMP in cells.
Step 2: Analyzing the Options.
- (A) Incorrect. Caffeine does not intercalate into DNA; it mainly affects cellular signaling pathways.
- (B) Correct. Caffeine inhibits the phosphodiesterase enzyme, increasing cAMP levels.
- (C) Incorrect. Caffeine does not directly inhibit the epinephrine response; instead, it stimulates it by increasing cAMP levels.
- (D) Incorrect. Caffeine increases, not reduces, the level of cAMP by inhibiting its breakdown.
Step 3: Conclusion.
Thus, the correct answer is (B).
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