Question:
Brown Tumor is seen in:
Brown Tumor is seen in:
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Brown color comes from hemosiderin in bone eaten away by high PTH.
Updated On: Jun 24, 2026
- Hypothyroidism
- Hyperthyroidism
- Hypoparathyroidism
- Hyperparathyroidism
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The Correct Option is D
Solution and Explanation
Step 1: A brown tumor is a focal bony lesion caused by excess parathyroid hormone. The high PTH drives strong osteoclastic bone resorption.
Step 2: The resorbed areas fill with fibrous tissue, blood, and clusters of giant cells. Old bleeding leaves hemosiderin, which gives the lesion its brown color, hence the name brown tumor. It is part of osteitis fibrosa cystica.
Step 3: This happens in hyperparathyroidism, where PTH is raised (primary, secondary, or tertiary). So option D is correct.
Step 4: Why the others are wrong. Hyperthyroidism speeds bone turnover and can cause osteoporosis, but it does not form brown tumors. Hypoparathyroidism and hypothyroidism both lower bone resorption, so the opposite of what a brown tumor needs.
Step 5: Bone in hyperparathyroidism also shows subperiosteal resorption and a salt-and-pepper skull, with raised serum calcium and low phosphate.
Answer: Hyperparathyroidism.
Step 2: The resorbed areas fill with fibrous tissue, blood, and clusters of giant cells. Old bleeding leaves hemosiderin, which gives the lesion its brown color, hence the name brown tumor. It is part of osteitis fibrosa cystica.
Step 3: This happens in hyperparathyroidism, where PTH is raised (primary, secondary, or tertiary). So option D is correct.
Step 4: Why the others are wrong. Hyperthyroidism speeds bone turnover and can cause osteoporosis, but it does not form brown tumors. Hypoparathyroidism and hypothyroidism both lower bone resorption, so the opposite of what a brown tumor needs.
Step 5: Bone in hyperparathyroidism also shows subperiosteal resorption and a salt-and-pepper skull, with raised serum calcium and low phosphate.
Answer: Hyperparathyroidism.
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