Question:
Besides its property of decreasing intraocular pressure, timolol is preferred in the treatment of glaucoma because it?
Besides its property of decreasing intraocular pressure, timolol is preferred in the treatment of glaucoma because it?
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Unlike pilocarpine it leaves the pupil unchanged.
Updated On: Jun 24, 2026
- Produces no miosis
- Possesses membrane stabilizing activity
- Increases outflow of aqueous humor
- Is a selective beta-adrenoceptor blocker
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The Correct Option is A
Solution and Explanation
Step 1: Timolol is a topical non-selective beta blocker that lowers intraocular pressure by reducing aqueous humor production by the ciliary body.
Step 2: Its key advantage over older miotic agents such as pilocarpine is that it does not change pupil size. It produces no miosis, so there is no fluctuation in intraocular tension, no induced myopia and no ciliary spasm or spasm of accommodation, making it more comfortable and convenient for once or twice daily use.
Step 3: Why the others are wrong - timolol works by decreasing aqueous formation, not by increasing outflow. It is a non-selective beta blocker, not a selective one. Although timolol has weak membrane stabilizing potential, this is not the clinical reason it is preferred for glaucoma.
Answer: Produces no miosis.
Step 2: Its key advantage over older miotic agents such as pilocarpine is that it does not change pupil size. It produces no miosis, so there is no fluctuation in intraocular tension, no induced myopia and no ciliary spasm or spasm of accommodation, making it more comfortable and convenient for once or twice daily use.
Step 3: Why the others are wrong - timolol works by decreasing aqueous formation, not by increasing outflow. It is a non-selective beta blocker, not a selective one. Although timolol has weak membrane stabilizing potential, this is not the clinical reason it is preferred for glaucoma.
Answer: Produces no miosis.
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