Step 1: Recall the drug class. Apixaban is a direct oral anticoagulant (DOAC).
Step 2: Identify the target. It directly and selectively inhibits activated factor Xa, blocking conversion of prothrombin to thrombin.
Step 3: Clinical use. It is used for treatment and prophylaxis of venous thromboembolism, including DVT and pulmonary embolism, and for stroke prevention in atrial fibrillation.
Step 4: Conclude and exclude. Option B (direct factor Xa inhibitor) is correct. It is not an antithrombin agent, a platelet activator, or a clotting factor.