Question:
Apixaban is
Apixaban is
Updated On: Jul 12, 2025
- Antithrombin inhibitor
- Direct Xa inhibitor
- Platelet activator
- Clotting Factor XII
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The Correct Option is B
Solution and Explanation
Apixaban is a pharmaceutical drug used in the prevention and treatment of thromboembolic disorders. It is classified as a Direct Xa inhibitor.
To understand why Direct Xa inhibitor the correct classification is, let's delve into its mechanism of action:
- Target: Apixaban directly targets and inhibits Factor Xa, an essential enzyme in the coagulation cascade.
- Function: Factor Xa plays a critical role in converting prothrombin to thrombin, a key step in the formation of blood clots.
- Effect: By inhibiting Factor Xa, Apixaban effectively reduces the formation of thrombin, thereby preventing clot formation.
This mechanism differentiates it from:
- Antithrombin inhibitors - These inhibit antithrombin, which is not Apixaban's target.
- Platelet activators - These stimulate platelet aggregation, opposite to Apixaban's purpose.
- Clotting Factor XII - This factor initiates the intrinsic pathway and is not the target of Apixaban.
Hence, Apixaban's role as a Direct Xa inhibitor is a crucial aspect of its therapeutic use in managing clotting disorders.
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